Manos PanAmerica is a Latin and North American fusion band that aims to reduce the gap between Latin and North America by playing its original and cover songs. It originated in 2023 in Saint Louis, Missouri, and is one of the few music projects in the city that incorporates various Latin genres and instruments into its performances.

Some of the genres Manos PanAmerica covers include cachimbos, cumbia, bossa nova, joropos, boleros, huaynos, bailecitos, rancheras, corridos, and salsa. Some of the instruments included in Manos PanAmerica are the charango, Colombian tiple, Venezuelan cuatro, quena, and zampoñas, among others.